{"id":20946,"date":"2024-06-24T14:06:04","date_gmt":"2024-06-24T05:06:04","guid":{"rendered":"https:\/\/nofia.net\/?p=20946"},"modified":"2024-06-24T14:06:04","modified_gmt":"2024-06-24T05:06:04","slug":"h5n1%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9%e3%81%8c%e5%a4%89%e7%95%b0%e3%81%ab%e3%82%88%e3%82%8a%e3%80%8c%e5%8f%97%e5%ae%b9%e4%bd%93%e7%b5%90%e5%90%88%e5%b9%85%e3%81%8c%e6%8b%a1%e5%a4%a7%e3%81%97","status":"publish","type":"post","link":"https:\/\/nofia.net\/?p=20946","title":{"rendered":"H5N1\u30a6\u30a4\u30eb\u30b9\u304c\u5909\u7570\u306b\u3088\u308a\u300c\u53d7\u5bb9\u4f53\u7d50\u5408\u5e45\u304c\u62e1\u5927\u3057\u305f\u300d\u3068\u3044\u3046\u8ad6\u6587"},"content":{"rendered":"<p>&nbsp;<\/p>\n<p><script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-6677469365582533\" crossorigin=\"anonymous\"><\/script><br \/>\n<!-- 0723b --><br \/>\n<ins class=\"adsbygoogle\" style=\"display: block;\" data-ad-client=\"ca-pub-6677469365582533\" data-ad-slot=\"4320035992\" data-ad-format=\"auto\"><\/ins><br \/>\n<script>\n     (adsbygoogle = window.adsbygoogle || []).push({});\n<\/script><\/p>\n<hr \/>\n<h3><span style=\"color: #cb0000;\">\u4e73\u725b\u95a2\u9023\u306eH5N1\u30a6\u30a4\u30eb\u30b9\u306e\u5358\u4e00\u5909\u7570\u306b\u3088\u308a\u53d7\u5bb9\u4f53\u7d50\u5408\u5e45\u304c\u62e1\u5927<\/span><\/h3>\n<p><span style=\"color: #808080; font-size: 10pt;\"><a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2024.06.22.600211v1 \" target=\"_blank\" rel=\"noopener\">biorxiv.org<\/a> 2024\/06\/22<\/span><\/p>\n<p><strong><span style=\"font-size: 10pt; color: #999999;\">A single mutation in dairy cow-associated H5N1 viruses increases receptor binding breadth<\/span><\/strong><\/p>\n<p><span style=\"color: #800000; font-size: 14pt;\"><strong>\u6982\u8981<\/strong><\/span><\/p>\n<p><span style=\"color: #000080;\">\u7cfb\u7d71\u7fa4 2.3.4.4b H5N1 \u304c\u3001\u7c73\u56fd\u306e\u4e73\u725b\u3067\u524d\u4f8b\u306e\u306a\u3044\u6d41\u884c\u3092\u5f15\u304d\u8d77\u3053\u3057\u3066\u3044\u308b\u3002<\/span><\/p>\n<p><span style=\"color: #000080;\">\u6700\u8fd1\u306e H5N1 \u30a6\u30a4\u30eb\u30b9\u304c\u53d7\u5bb9\u4f53\u306e\u5229\u7528\u65b9\u6cd5\u3092\u5909\u3048\u3066\u3044\u308b\u304b\u3069\u3046\u304b\u3092\u628a\u63e1\u3059\u308b\u305f\u3081\u3001\u904e\u53bb\u304a\u3088\u3073\u6700\u8fd1\u306e 2.3.4.4b H5N1 \u30a6\u30a4\u30eb\u30b9\u304b\u3089\u7d44\u63db\u3048\u30d8\u30de\u30b0\u30eb\u30c1\u30cb\u30f3<span style=\"color: #808080;\">\uff08HA \/ \u8d64\u8840\u7403\u51dd\u96c6\u7d20\uff09<\/span>\u3092\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u3057\u3001\u672b\u7aef\u30b7\u30a2\u30ea\u30f3\u9178\u3092\u6301\u3064\u7570\u306a\u308b\u30b0\u30ea\u30ab\u30f3<span style=\"color: #808080;\">\uff08\u7cd6\u9396\uff09<\/span>\u3078\u306e\u7d50\u5408\u3092\u8abf\u3079\u305f\u3002<\/span><\/p>\n<p><span style=\"color: #000080;\">\u4e73\u725b\u306e\u6d41\u884c\u304b\u3089\u5206\u96e2\u3057\u305f A\/Texas\/37\/2024 \u7531\u6765\u306e H5 \u306f\u3001\u904e\u53bb\u304a\u3088\u3073\u6700\u8fd1\u306e 2.3.4.4b H5N1 \u30a6\u30a4\u30eb\u30b9\u3068\u6bd4\u8f03\u3057\u3066\u3001\u9ce5\u985e\u53d7\u5bb9\u4f53\u3067\u3042\u308b\u672b\u7aef a2,3 \u30b7\u30a2\u30ea\u30f3\u9178\u3092\u6301\u3064\u30b0\u30ea\u30ab\u30f3\u3078\u306e\u7d50\u5408\u5e45\u304c\u5e83\u304c\u3063\u3066\u3044\u308b\u3053\u3068\u3092\u767a\u898b\u3057\u305f\u3002\u30d2\u30c8\u306e\u5b63\u7bc0\u6027\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30a6\u30a4\u30eb\u30b9\u304c\u4f7f\u7528\u3059\u308b\u53d7\u5bb9\u4f53\u3067\u3042\u308b a2,6 \u30b7\u30a2\u30ea\u30f3\u9178\u3078\u306e\u7d50\u5408\u306f\u89b3\u5bdf\u3055\u308c\u306a\u304b\u3063\u305f\u3002<\/span><\/p>\n<p><span style=\"color: #000080;\">\u53d7\u5bb9\u4f53\u7d50\u5408\u90e8\u4f4d\u306e\u5916\u5074\u306b\u3042\u308b\u5358\u4e00\u306e\u5909\u7570 T199I \u304c\u3001\u53d7\u5bb9\u4f53\u7d50\u5408\u90e8\u4f4d\u306e\u67d4\u8edf\u6027\u3092\u9ad8\u3081\u3001\u7d50\u5408\u5e45\u306e\u62e1\u5927\u306e\u539f\u56e0\u3067\u3042\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u305f\u3002<\/span><\/p>\n<p><span style=\"color: #000080;\">\u3053\u308c\u3089\u306e\u30c7\u30fc\u30bf\u3092\u7dcf\u5408\u3059\u308b\u3068\u3001\u6700\u8fd1\u306e H5N1 \u30a6\u30a4\u30eb\u30b9\u306f\u53d7\u5bb9\u4f53\u7d50\u5408\u306e\u5e45\u304c\u62e1\u5927\u3057\u3066\u304a\u308a\u3001\u305d\u308c\u304c H5N1 \u306b\u611f\u67d3\u3057\u305f\u5bbf\u4e3b\u306e\u7bc4\u56f2\u3084\u7d30\u80de\u306e\u7a2e\u985e\u306b\u5f71\u97ff\u3092\u53ca\u307c\u3059\u53ef\u80fd\u6027\u304c\u3042\u308b\u3053\u3068\u304c\u308f\u304b\u308b\u3002<\/span><\/p>\n<p><script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-6677469365582533\" crossorigin=\"anonymous\"><\/script><br \/>\n<!-- 0723b --><br \/>\n<ins class=\"adsbygoogle\" style=\"display: block;\" data-ad-client=\"ca-pub-6677469365582533\" data-ad-slot=\"4320035992\" data-ad-format=\"auto\"><\/ins><br \/>\n<script>\n     (adsbygoogle = window.adsbygoogle || []).push({});\n<\/script><\/p>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp; \u4e73\u725b\u95a2\u9023\u306eH5N1\u30a6\u30a4\u30eb\u30b9\u306e\u5358\u4e00\u5909\u7570\u306b\u3088\u308a\u53d7\u5bb9\u4f53\u7d50\u5408\u5e45\u304c\u62e1\u5927 biorxiv.org 2024\/06\/22 A single mutation in dairy cow-associated H5N1 vi &hellip; <a href=\"https:\/\/nofia.net\/?p=20946\" class=\"more-link\">\u7d9a\u304d\u3092\u8aad\u3080 <span class=\"screen-reader-text\">H5N1\u30a6\u30a4\u30eb\u30b9\u304c\u5909\u7570\u306b\u3088\u308a\u300c\u53d7\u5bb9\u4f53\u7d50\u5408\u5e45\u304c\u62e1\u5927\u3057\u305f\u300d\u3068\u3044\u3046\u8ad6\u6587<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":20697,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[57],"tags":[],"class_list":["post-20946","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"_links":{"self":[{"href":"https:\/\/nofia.net\/index.php?rest_route=\/wp\/v2\/posts\/20946","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nofia.net\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nofia.net\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nofia.net\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/nofia.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=20946"}],"version-history":[{"count":1,"href":"https:\/\/nofia.net\/index.php?rest_route=\/wp\/v2\/posts\/20946\/revisions"}],"predecessor-version":[{"id":20947,"href":"https:\/\/nofia.net\/index.php?rest_route=\/wp\/v2\/posts\/20946\/revisions\/20947"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nofia.net\/index.php?rest_route=\/wp\/v2\/media\/20697"}],"wp:attachment":[{"href":"https:\/\/nofia.net\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=20946"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nofia.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=20946"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nofia.net\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=20946"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}